Yerba mate was has been used as a beverage since the time of the ancient Indians of Brazil and Paraguay. In addition to its standing as a popular beverage, yerba mate is used as a tonic, diuretic, and as a stimulant to reduce fatigue, suppress appetite, and aid gastric function in herbal medicine systems throughout South America. It also has been used as a depurative (to promote cleansing and excretion of waste). In Brazil, mate is said to stimulate the nervous and muscular systems and is used for digestive problems, renal colic, nerve pain, depression, fatigue, and obesity. A poultice of the leaves also is applied topically to anthrax skin ulcers (for which mate's tannin content - highly astringent - may be the reasoning behind this use).Yerba mate also has a long history of use worldwide. In Europe it is used for weight loss, physical and mental fatigue, nervous depression, rheumatic pains, and psychogenic- and fatigue-related headaches. In Germany it has become popular as a weight-loss aid. Yerba mate is the subject of a German monograph which lists its approved uses for mental and physical fatigue. In France yerba mate is approved for the treatment of asthenia (weakness or lack of energy), as an aid in weight-loss programs, and as a diuretic. It also appears in the British Herbal Phamacopoeia (1996) and indicated for the treatment of fatigue, weight loss, and headaches. In the U.S., it has been recommends for arthritis, headache, hemorrhoids, fluid retention, obesity, fatigue, stress, constipation, allergies, and hay fever, cleansing the blood, tone the nervous system, retards aging, stimulates the mind, controls the appetite, stimulates the production of cortisone, and is believed to enhance the healing powers of other herbs. Yerba mate now is cultivated in India, and the Indian Ayurvedic Phamacopoeia lists mate for the treatment of psychogenic headaches, nervous depression, fatigue, and rheumatic pains.

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